Integrated understanding of human multi-sensing networks and elucidation of their control mechanisms


The sensory organs (eyes, ears, nose, mouth), the skin over the entire body, the deep internal organs (liver, stomach and intestines, etc.), and the peripheral nerves, which are widely distributed through these organs, work in collaboration to maintain the functions of the entire body. The deterioration and loss of sensory functions induced by aging, stress, and environmental factors and peripheral neuropathy are risk factors for health impairment and the onset of chronic diseases. An integrated understanding of multi-sensing physiological mechanisms comprising the biosensor system and the peripheral nerve network leads to improve quality of life (QOL) and extends healthy life expectancy through the development of new treatment methods that target the various organs  and diseases.

This Target aims at the understanding of the multi-sensing system comprising the biosensor system and the peripheral nerve network, the explication of pathologies, technological development for the visualization and quantification of their activity status, the development of prevention and therapy, especially personalized medicines, medical equipment, and minimally invasive medical devices. It also aims at the creation of innovation seeds through the expansion of the whole body multi-sensing functions and application of advanced sensing.


Office for Basic Research Projects, Basic Research Promotion Division, Research Promotion Bureau